Manifestações Bucais associadas à imunossupressão em pacientes submetidos a transplante de Coração

Manifestações Bucais associadas à imunossupressão em pacientes  submetidos a transplante de Coração
Oral manifestations associated with immunosuppression  in patients undergoing heart transplant

Rev Soc Cardiol Estado de São Paulo. 2014;24(1 Supl A):39-43
RSCESP (72594)-2097

Paulo sérgio da silva santos
Paola Ferreira teixeira
karin sá Fernandes

A condição de imunossupressão de pacientes transplantados  cardíacos possibilita o surgimento de manifestações bucais  importantes que representam risco para o sucesso do  transplante cardíaco. A avaliação e o acompanhamento  odontológico desses pacientes são fundamentais na prevenção
dessas manifestações bucais e infecções sistêmicas. Por meio  do relato dos casos clínicos de três pacientes transplantados  cardíacos, apresentamos e discutimos as condições clínicas e  as opções terapêuticas das manifestações bucais mais comuns  neste grupo de pacientes.

Oral care of the patient with liver failure, pretransplant—a retrospective study

Oral care of the patient with liver  failure, pretransplant—a retrospective study
Jeffery L. Hicks, DDS*
Professor, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
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Special Care in DentistryEarly View, Article first published online: 19 MAY 2014

Liver failure patients seeking liver transplant in our teaching hospital undergo dental clearance by our Hospital Dentistry Department. A retrospective analysis of 500 patient dental charts was performed. All patients were evaluated previously by physicians and the medical diagnosis of liver failure for each patient was determined. Patients were examined and a treatment plan was formed consisting of the oral care required prior to dental clearance for liver transplant. An oral care treatment algorithm was constructed that, along with clinical parameters, guided the oral care in the pretransplant period. The oral care necessary to clear the patient for transplant was completed for each patient. Besides computing the average cost of oral care necessary to clear patients, analyses were performed to look for correlations among laboratory tests required before oral surgical procedures.

Curso de Aperfeiçoamento em Odontologia Hospitalar - FUNBEO

Julho está chegando e com ele a 3ª turma do Curso de Aperfeiçoamento em Odontologia Hospitalar da FUNBEO junto à Faculdade de Odontologia de Bauru, Universidade de São Paulo. Ainda há vagas!!!! Acesse o site da FUNBEO e conheça mais detalhes e informações sobre o curso:
http://www.funbeo.com.br/do/Curso_view/128/aperfeicoamento_em_odontologia_hospitalar

Viral Opportunistic Infections in Organ and Tissue Transplanted Patients: Comparison between Clinical Examination and PCR

International Journal of Clinical Dentistry ISSN: 1939-5833
Volume 7, Number 1 © Nova Science Publishers, Inc.
VIRAL OPPORTUNISTIC INFECTIONS IN ORGAN
AND TISSUE TRANSPLANTED PATIENTS:
COMPARISON BETWEEN CLINICAL EXAMINATION
AND PCR
Paulo Sérgio da Silva Santos, DDS, MSc, PhD1,
José Endrigo Tinoco-Araujo, MSc, PhDc2, Ana Paula Bloise, DDS3,
and José Roberto Pereira Lauris, MSc, PhD4
1Professor, Stomatology Department, Bauru School of Dentistry,
University of São Paulo, Bauru, Brazil
2Graduate student, Stomatology Department, Bauru School of Dentistry,
University of São Paulo, Bauru, Brazil
3Paulista University, São Paulo, Brazil
4Professor, Department of Paedodontics, Orthodontics and Public Health of Dentistry,
Bauru School of Dentistry, University of São Paulo, Bauru, Brazil
ABSTRACT
Purpose: To evaluate correlation between clinical suspicion and laboratory diagnosis
of viral opportunistic infections in transplanted patients.
Methods: We assessed 29 patients with oral infections with a clinical aspect of viral
lesions. We scraped the oral lesions, collected secretions using swab and sent samples to
the molecular biology laboratory for PCR according to the clinical diagnostic hypotheses.
Results: We found 44.8% of cases suspected of having HSV, 6.9% of CMV and in
48.3% there was doubts about the diagnosis. The PCR was positive for HSV in 34.5% of
cases, for CMV in 6.9%, for both HSV and CMV in 10.3% and negative in 46.7% of the
cases.
The sensitivity of clinical examination was 100% for both HSV and CMV, but the
possibility of having the infection by HSV or CMV was respectively 44% and 25%. We
suggest that clinical examination is not sufficient to establish the final diagnosis of viral
lesions in transplanted patients, making it necessary for exams of high reliability as the
PCR.

Oral Mucositis: Prevention and Treatment

Héliton Spindola Antunes1, Paulo Sérgio da Silva Santos2,
Fábio Luiz Coracin3, Geisa Badauy Lauria Silva4,
Luiz Antonio de Souza5, and Luiz Alberto Soares Valente Jr.6*
1DDS, PhD of the Clinical Research Coordination,
National Cancer Institute of Brazil (INCA)
2DDS, PhD, Professor of the Stomatology Department, Bauru School of Dentistry,
University of Sao Paulo, Brazil
3DDS, PhD of the Bone Marrow Transplant Service,
Clinicas Hospital from School of Medicine – University of Sao Paulo;
Professor of Pathology and Oral Medicine in Nove de Julho University, Sao Paulo, Brazil
4DDS, MSc of the Bone Marrow Transplant Service and of Pediatric Oncology in Araújo
Jorge Hospital (HAJ/ACCG)
5DDS of the Blood Center in Santa Catarina (HEMOSC)
6DDS, MSc of the Dentistry Division in Clinicas Hospital,
School of Medicine – University of Sao Paulo, Brazil
ABSTRACT
Oral Mucositis (OM) is one of the main complications of patients submitted to the
oncologic treatment. The incidence of oral mucositis varies, and is intimately related to
the toxicity of chemotherapy and radiotherapy protocol. Prolonged or profound oral
mucositis leads to significant pain and morbidity and depending on its progression, it may
be necessary to interrupt the treatment followed or not by hospitalization.
OM occurs approximately in seven to ten days after chemotherapy and from the
second week of radiotherapy. Although it is a toxic reaction and inflammation that is
studied for a long time, the molecular and cell mechanisms described recently may
contribute for the appearance of new protocols of prevention. In the context of options
studied in the prevention of OM, there are efficient alternatives as cryotherapy, growth
factor of keratinocytes and the low-level lasers that promote a reduction in the incidence
of OM and pain during the period of the oncologic treatment.
The aim of this chapter was to investigate the available literature regarding OM,
searching relevant articles and eligible clinical trials in order to obtain additional
information about prevention and treatment interventions to OM.

 Members of the Committee of Dentistry from the Brazilian Association of Hematology and Hemotherapy.